Dispositivo para Microextração Líquido–Líquido in situ e Eletroanálise

Sample preparation, specially, miniaturized extraction procedure, such as Liquid-liquid microextraction (LLME), have received considerable attention. This is due their simplicity of handling, low sample consumptions, high speed, reduced processing cost and time, negligible volume of the extractor solvent, as well as reduced residue generation. The progress in the scientific research allowed the pre concentration of analytes from very dilute samples,without using toxic organic solvents, and meet with the principles of trace analysis and the green chemistry [1]. Here, we demonstrate the applicability of a new procedure, based on adaptation of previously published work that detects three fluoroquinolone (FQs) in tap water samples, concomitantly [2]. In this context, the compact device include an adaptation of an electrochemical cell (containing conventional electrodes: glass carbon as working electrode, Ag/AgClKClsat.as reference electrode and Pt as counter electrode) to in situmake the extraction usinga non-toxic extractor solvent, called deep eutectic solvent (DES). The proposed approach combine many steps involved in the conventional LLME, which the samples hould be processed to eliminate any matrix concomitant, however, we perform this procedurein a unique device.The interferences —that could hinderthe accurate measurement of the peak current—can bee liminated forfurther preconcentratetarget analyte in order to achieve the desired quantitation limit. The device allowed us demonstratesthe unique application of anelectroanalytical technique coupled with sample preparation for in situ extraction and preconcentration of the emerging pollutant ciprofloxacin (CIPRO) from tap water sample(Fig. 1).This combined feature shown high enrichment factor able to determineCIPRO at 10 nmol L-1with total analysis time of 10 minutes,between the extraction and quantification, whichthe recovery values wasremarkably close to 100%.