Antiviral Medicinal Plants Natural Products Database (avMpNp DB): an antiviral compound database of natural products.

Vol 9, 2023 - 167430
Poster
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Abstract

The aims of the present study are the development of Antiviral Medicinal Plants Natural Products Database (avMpNp DB) and the evaluation of the enzymatic inhibition of SARS-CoV-2 Mpro and PLpro in vitro of promising phenolics identified by this DB. The IC50 obtained for caffeic and gallic acid against SARS-CoV-2 Mpro was very promising, with values of 15.795 ± 0.155 μM and 6.308 ± 0.296 μM, respectively.

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Institutions
  • 1 Universidade Federal de Minas Gerais
  • 2 University of California San Diego
Track
  • 1. Biodiversity and Natural Products
Keywords
database; Antiviral; Natural products; Inhibitory concentration