Seriniquinone as a Challenging Drug Model for Nanoformulation Process of Natural Products

Vol 9, 2023 - 164673
Poster
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Abstract

This work demonstrates the nanoformulation attempts of poor water-soluble seriniquinone, a secondary metabolite of the marine bacteria Serinicoccus sp. Distinct nanosystems, recommended or described for other lipophilic drugs, were developed. Only poly (D,L-lactide-co-glycolide) nanoparticles were able to encapsulate seriniquinone and enable the first outlines of in vivo studies.

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Institutions
  • 1 Universidade de São Paulo
  • 2 Universidade Federal de São Paulo
Track
  • 2. Biological and Pharmacological Activity of Natural Products
Keywords
poor-aqueous solubility; drug formulation; Nanobiotechnology