Synthesis and Biological Activities of Esters Derived from Friedelinol

Vol 9, 2023 - 162774
Poster
Download
Favorite this paper
How to cite this paper?
Abstract

The objective was to synthesize different esters from the 3α and 3β isomers of the triterpene friedelinol and evaluate their anti-leukemic and anticholinesterase activities. Eight esters were synthesized. All of them showed low anti-leukemic activity against the THP-1 and K-562 cell lines. Overall, all esters exhibited good percentages of acetylcholinesterase inhibition at least at one of the tested concentrations.

Share your ideas or questions with the authors!

Did you know that the greatest stimulus in scientific and cultural development is curiosity? Leave your questions or suggestions to the author!

Sign in to interact

Have a question or suggestion? Share your feedback with the authors!

Institutions
  • 1 Universidade Federal de Minas Gerais
Track
  • 7. Organic Synthesis and Structural Modification
Keywords
friedelinol; ESTERIFICATION; antileukemic activity; Anticholinesterase activity