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In this project 8 strains of Streptomyces, isolated from fungus-growing ants of Amazonian region, were evaluated for bioactive natural products against Leishmania infantum and other pathogens. The results include a variety of compounds, especially antifungals, active against Leishmania and Escovopsis, a specialized parasite fungus of ants, revealing the importance of this type of compound in the relationship between ants and actinobacteria. This is the first record of echinomycin in this system.
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