According to the World Health Organization, in the context of the recently endorsed Global Technical Strategy for Malaria 2016-2030, which sets the ambitious target of eliminating malaria from at least 35 countries by 2030, P. vivax presents a major challenge. In 2013, it was responsible for an estimated 16 million cases globally and nearly half of cases outside Africa. Therefore, malaria eradication requires tackling all parasite species that cause human infection. In Manaus in 2017 we will review the most recent advances on this parasite and debate the major bottlenecks in P. vivax malaria elimination. Now it is #timetogoforvivax.