Conservation analysis of resistance promoting channels from Pseudomonas aeruginosa

Introduction: Pseudomonas aeruginosa is a Gram-negative opportunistic pathogenic bacterium found in various locations, from soil to surgical instruments. It exhibits significant antimicrobial resistance, an emerging concern that could cause 10 million deaths annually by 2050. One of the mechanisms conferring resistance in P. aeruginosa is the efflux systems, such as the Resistance-Nodulation-Division (RND) system.