Synthesis, characterization and in vitro antiviral activity over Zika virus of a cobalt(II) complex with an amantadine-Schiff base.

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Abstract

This work describes the synthesis of a Co(II) complex with a Schiff base derived from amantadine and salicylaldehyde with a 1:2 metal:ligand ratio characterized by spectroscopic and elemental analysis and its antiviral activity against the Zika virus in Vero E6 cells.

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Institutions
  • 1 Instituto de Química - UNICAMP
  • 2 Federal University of Uberlândia
  • 3 Instituto de Física de São Carlos
  • 4 Institute of Chemistry - UNICAMP
Track
  • TL03 - Biological and Medicinal Inorganic Chemistry
Keywords
antiviral
cobalt(II)
aminoadamantanes