GC-MS-based molecular networking and anticholinesterase activity of Worsleya procera leaves

Vol 9, 2023 - 167370
Poster
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Abstract

The molecular network based on gas chromatography-mass spectrometry constructed from the alkaloid-enriched fractions obtained with different solvents showed that the chemical profiles were similar. Among the groups tested, there was no significant difference in anticholinesterase potential, except for the FE-HEP fraction. Further analysis is needed, but the annotation of the compounds can help to understand the biological response and rationalize future analysis.

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Institutions
  • 1 Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP), Universidade de São Paulo (USP)
  • 2 Centro de Ciências Exatas, naturais e da Saúde (CCENS), Universidade Federal do Espírito Santo (UFES)
Track
  • 2. Biological and Pharmacological Activity of Natural Products
Keywords
Amaryllidaceae; GNPS; Alkaloids; Neurodegenerative diseases