Cave dwelling Bacteria as a Source of the Benzodazepine Alkaloids

Vol 9, 2023 - 166987
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Abstract

Different groups of cave-dwelling bacteria produced pyrrolobenzodiazepine alkaloid derivatives to respond to oligotrophy and high iron content substrates. Molecular Network analysis indicates an interesting cluster of new analogs.

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Institutions
  • 1 Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP), Universidade de São Paulo (USP)
  • 2 Instituto Tecnológico Vale
  • 3 Universidade de São Paulo
Track
  • 1. Biodiversity and Natural Products
Keywords
Caves; Metabolomics; Proteobacteria; Firmicutes; Oligotrophy