Pseudovibriamides, a novel family of ureido-containing peptides

Vol 8, 2021 - 140986
e-Poster
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Abstract

Pseudovibrio brasiliensis is a new species of marine alpha-proteobacteria found only in healthy sponges. Herein we present a reverse genetics method for this strain and identified the products of a biosynthetic gene cluster (BGC) highly conserved among Pseudovibrio isolates. MS-guided fractionation led the isolation of 12 new ureido-containing peptides encoded by this BGC, named pseudovibriamides.

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Institutions
  • 1 Universidade de São Paulo
  • 2 University of Illinois at Chicago
  • 3 Universidade Federal de São Carlos
Track
  • 4. Biosynthesis and Molecular Biology of Natural Products
Keywords
non-ribosomal peptides
ureido-linkage
Pseudovibrio