Phytochemicals from Aristolochia elegans seeds, antiplasmodial activity evaluation, and quantification of aristolochic acid I in teas by 1H-qNMR

Vol 8, 2021 - 142490
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Abstract

Aristolochia elegans seeds are used to treat malaria.
Extracts of seeds were evaluated against chloroquine resistant Plasmodium falciparum strain W2, and they were inactive when tested up to 50 μg/mL.
Aristolochic acid I was the major compound in A. elegans seeds.
This nitrophenanthrene derivative was quantified in the extracts by 1H-qNMR.

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Institutions
  • 1 Universidade Federal da Grande Dourados
  • 2 Universidade Federal de São Carlos
  • 3 Universidade Estadual de Feira de Santana
  • 4 Fundação Oswaldo Cruz
  • 5 Universidade Federal do Amazonas
Track
  • 2. Biological and Pharmacological Activity of Natural Products
Keywords
Ethnobotany
malária
nephrotoxicity
mutagenicity
Aristolochiaceae