In vitro evaluation of anti-Trypanosoma cruzi activity of y-Lactones from Persea americana

Vol 8, 2021 - 142384
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*Prospection of new bioactive compounds from Brazillian flora
*Lincomolide D (1) and isolinderanolide E (2) - as well as one new y-lactone perseanolide (3), were isolated from Persea americana (Lauraceae)
*Perseanolide (3) displayed superior activity than the positive control benznidazole

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  • 1 Universidade Federal do ABC
  • 2 Adolfo Lutz
Chagas disease
Persea americana
Trypanosoma cruzi