High-Resolution Inhibition Profiling for Screening of Nucleoside Hydrolase Inhibitors in Moringa oleifera Lamarck

Vol 8, 2021 - 143040
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Abstract

Herein we report the preparation of different extracts from Moringa oleifera Lamarck with their further screening of LdNH inhibitors. High-resolution LdNH inhibition profiling combined with ligand fishing assays have been used to investigate the most potent extract.

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Institutions
  • 1 Universidade Federal Fluminense
  • 2 Universidade Federal de Goiás
  • 3 Universidade Federal do Rio de Janeiro
Track
  • 6. Medicinal Chemistry
Keywords
screening assays
nucleoside hydrolase
MORINGA
enzymatic inhibitors