Cytotoxic anthraquinones from a Brazilian cave soil-derived fungus Aspergillus sp. SDC28

Vol 8, 2021 - 140673
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Abstract

Investigation of the EtOAc extract from the growth medium produced by a soil-derived fungus, Aspergillus sp. SDC28, isolated from a Brazilian cave, yielded three compounds versiconol, versicolorin C and bisdeoxydothistromin. The structures were established by means of NMR and mass spectroscopic data. Both versiconol and versicolorin C were also evaluated for their cytotoxic activity against human ovarian cancer cells (OVCAR3)

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Institutions
  • 1 Universidade de São Paulo
  • 2 Universidade Federal de São Carlos
  • 3 Universidade Federal Fluminense
  • 4 Universidade Federal de São Paulo
  • 5 University of Illinois
Track
  • 2. Biological and Pharmacological Activity of Natural Products
Keywords
Brazilian cave
anthraquinones
soil-derived fungus
Aspergillus
cytotoxicity