Chemical profile, antioxidant, antiproliferative and anti-inflammatory activity of Leandra aurea (Melastomataceae) flowers

Vol 8, 2021 - 143015
e-Poster
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Abstract

Leandra aurea (Melastomataceae) flowers extract (CE) was evaluated for its chemical profile, antioxidant, antiproliferative (in vitro) and anti-inflammatory (in vivo) activities. HPLC profile shows CE contains ellagitannins, triterpenes and flavonoids. CE was active against DPPH and ABTS radicals and had ferrous chelating capacity. CE has strong antiproliferative activity against glioma and breast cells and moderate activity against NCI-H460 cells. CE inhibited 83.6% of myeloperoxidase enzyme.

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Institutions
  • 1 Universidade Estadual de Maringá
  • 2 Universidade Estadual de Campinas
Track
  • 1. Biodiversity and Natural Products
Keywords
Melastomataceae
HPLC-QTOF-MS/MS
anti-inflammatory
antiproliferative
Antioxidant