5’-deoxy-5’-methylthioadenosine phosphorylase immobilized on the magnetic beads as a new tool for screening of inhibitors

Vol 8, 2021 - 142507
e-Poster
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Abstract

Herein we report the immobilization and kinetic characterization of the MTAP on to magnetic particles to prospect ligands in natural chemical libraries by affinity-based assay.

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Institutions
  • 1 Universidade Federal de São Carlos
  • 2 Universidade Federal Fluminense
Track
  • 6. Medicinal Chemistry
Keywords
Schistosomiasis
inhibitors screening
enzyme immobilization
MTAP