β-Carboline Alkaloids and Anticandidal and Antiproliferative Activities of the Endemic Brazilian Rubiaceae Palicourea minutiflora

Vol 8, 2021 - 142543
e-Poster
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Abstract

Bioguided phytochemical study of the chloroform:ethyl acetate (1:1) (CEAF) fraction obtained from Palicourea minutiflora resulted in the isolation of three β-carboline alkaloids. The 4-N-oxide-haman showed moderate anticandidal activity. The CEAF fraction exhibited potential antiproliferative effect against breast (MCF-7) and ovarian (OVCAR-3) cell lines and the highest antifungal activity in C. albicans.

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Institutions
  • 1 Universidade Estadual de Maringá
  • 2 Universidade Estadual de Campinas
Track
  • 5. Recent Advances in the Isolation and Structure Elucidation of Secondary Metabolites
Keywords
Palicourea minutiflora
Rubiaceae
Alkaloids